XCUSE ME is about two friends Chantu [Sharman Joshi] and Bantu [Saahil Khan], who are up to some pranks all the while. After completing their graduation, the two join a hotel in the catering department.

But it's not an easy ride for Chantu and Bantu, as they encounter the hotel manager [Saurabh Shukla], the housekeeping department head [Mushtaq Khan], who robs the guests of their valuable belongings, a fraud who claims to be the Maharani of Janakpur [Shashi Sharma] and the two owners of the hotel, who are absolute weirdos. Ironically, Chantu and Bantu fall in love with the daughters of the hotel – Chundadi [Jaya Seal] and Mundadi [Sonali Joshi]. But there's a catch!

The fathers of the two girls – the owners – throw a challenge on Chantu and Bantu to revive their resort in Goa, which had been forced to shut down since a notorious gangster Pedro [Pratap Singh] and his brother Sahiba operate their own resort in the same vicinity. Chantu and Bantu accept the challenge and not only do they take the gangster to task, but also win the whole-hearted approval of their prospective fathers-in-law in the end. On the whole, XCUSE ME is a fair entertainer.